Vision
IRRE makes replication firstIclass by matching original authors, independent labs, and funders to validate important findings quickly and transparently. The vision is a healthier research economy where incentives reward verification, null results are visible, and policy or product decisions rest on sturdier evidence. Sponsors gain a portfolio view of what works, what generalizes, and where further investment is warranted.
Problem
Replication suffers from misaligned incentives, scarce funding, and scattered documentation. Protocols, data dictionaries, and analysis scripts live across PDFs, notebooks, and private emails; new teams waste months rebuilding context. Journals and funders lack comparable process metrics to track rigor. As a result, replication remains rare or slow, reinforcing publication bias and fragile conclusions with outsized downstream cost.
Solution
Cosolvent standardizes briefs, timelines, and artifact checklists. With LLM+RAG, teams upload papers, preregistration PDFs, code, and data samples; natural-language queries pull the exact protocol steps, variable definitions, or exclusion rules with citations. ClientSynth simulates replication cohorts—varying sample sizes, sites, and analysis choices—so sponsors can preview risk, likely timelines, and decision points before committing funds. Clearer expectations accelerate starts and reduce friction between authors and replicators.
Business Model
IRRE earns from platform and coordination fees, with funders underwriting thematic replication challenges. Journals and societies can license dashboards that summarize throughput, outcome distributions, and methodological patterns (governed and privacy-preserving), building a sustainable path for sponsors to improve research quality at scale.